Overview
FAVORGEN™ FFPE DNA Purification Kit provides a rapid method for the isolation and purification of genomic DNA from formalin-fixed paraffin-embedded (FFPE) tissue samples. Using formalin to fix tissues leads to crosslinking of the nucleic acids and proteins, and the process of embedding the tissue samples can also lead to fragmentation of the nucleic acids over time. FAVORGEN™ FFPE DNA Purification Kit provides conditions that allow for the partial reversing of the formalin modifications, resulting in a high quality and yield of nucleic acids. The DNA is purified from other cellular components without the use of phenol or chloroform. The purified genomic DNA is of the highest integrity, and can be used in a number of downstream applications including qPCR, mutation screening, microarray analyses, sequencing, Southern blotting and SNP analysis.